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Systane® Nighttime Lubricant Eye Ointment is a preservative-free formula designed to provide intense moisture and protection for overnight dry eye relief. This soothing ointment forms a protective layer over the eyes, reducing irritation, dryness, and discomfort while you sleep.
✔ Long-lasting overnight relief – stays on longer than traditional eye drops.
✔ Preservative-free – gentle on sensitive eyes.
✔ Helps prevent overnight moisture loss for healthier eyes in the morning.
Get the soothing protection your eyes need while you sleep with Systane® Nighttime Lubricant Eye Ointment. Order today for lasting hydration and comfort!
Fast, tracked delivery
Your order typically arrives within 3–5 business days within the contiguous US, with tracking included on every shipment.
Easy 30-day returns
Changed your mind? Return unopened items in their original packaging within 30 days for a refund to your original payment method.
Some items are final sale
For health and safety, opened prescription products and contact lenses can't be returned.

$18.95
The most important element in managing my dry eyes
Of all the new habits I need to adopt now that my eyes are so dry, using this ointment before I go to sleep is the most helpful. I don't wake up with my eyes stuck to the inside of my eyelids any more and I think the ointment prevents the damage I was doing to the surface of my eyes. It's a little tricky to use and the ointment wants to keep coming out before you have a chance to put the cap back on. It does make everything blurry so you can't read or anything after you put it in--you have to do it right before going to sleep. My eyes have been rejecting most drops but I don't have a problem with this ointment.
nighttime systane
seems to make my eyes moist for 15 hours plus
Makes a difference
I was surprised that this ointment makes my eyes feel so much better.
Dry eye relief
The Systane ointment elimisted dry eye pain during the night and in the morning
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