Bion Tears Lubricant Eye Drops is an advanced tear substitute especially formulated and packaged for persistent dry eye conditions requiring frequent therapy. How To Use: Make sure container is intact before use. To open, COMPLETELY TWIST OFF TAB. Do not pull off. Instill 1 or 2 drops in the affected eye(s) as needed. Throw away container. Do not reuse. Once opened, discard. all four containers within a pouch must be used within four days of opening the pouch. Active ingredients: Dextran 70 0.1% (purpose: lubricant), Hypromellose 0.3% (purpose: lubricant)